Total parathyroidectomy without autotransplantation in dialysis patients and renal transplant recipients, long-term follow-up evaluation.
Am J Surg
; 198(2): 178-83, 2009 Aug.
Article
em En
| MEDLINE
| ID: mdl-19217601
ABSTRACT
BACKGROUND:
Persistent secondary hyperparathyroidism not responding to medication is treated successfully with surgical excision of parathyroid glands (total parathyroidectomy [PTX]). PTX without autotransplantation of parathyroid glands excludes the risk for recurrence of hyperparathyroidism.METHODS:
During the years 2002 to 2005, 36 total parathyroidectomies were performed in 33 patients 21 dialysis patients because of end-stage renal disease and 12 renal transplant recipients.RESULTS:
PTX without autotransplantation was performed successfully in 33 patients, whereas 3 patients were reoperated for remaining parathyroid glands. Immediate improvement of clinical symptoms and a decrease of serum calcium and parathormone levels were observed after surgical procedures. Oral replacement treatment with vitamin D (1a-calcidiol) and calcium was commenced and long-term follow-up evaluation (23.5 +/- 7.6 mo) showed that calcium homeostasis was controlled adequately.CONCLUSIONS:
PTX without autotransplantation is a safe and effective surgical procedure for the treatment of resistant secondary hyperparathyroidism with immediate response of clinical symptoms. Replacement treatment with vitamin D and calcium provides satisfactory coverage of individual needs.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paratireoidectomia
/
Diálise Renal
/
Transplante de Fígado
/
Hiperparatireoidismo Secundário
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article