Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients.
Opt Express
; 17(5): 3884-902, 2009 Mar 02.
Article
em En
| MEDLINE
| ID: mdl-19259230
ABSTRACT
"Diffuse correlation spectroscopy" (DCS) is a technology for non-invasive transcranial measurement of cerebral blood flow (CBF) that can be hybridized with "near-infrared spectroscopy" (NIRS). Taken together these methods hold potential for monitoring hemodynamics in stroke patients. We explore the utility of DCS and NIRS to measure effects of head-of-bed (HOB) positioning at 30 degrees , 15 degrees , 0 degrees , -5 degrees and 0 degrees angles in patients with acute ischemic stroke affecting frontal cortex and in controls. HOB positioning significantly altered CBF, oxy-hemoglobin (HbO(2)) and total-hemoglobin (THC) concentrations. Moreover, the presence of an ipsilateral infarct was a significant effect for all parameters. Results are consistent with the notion of impaired CBF autoregulation in the infarcted hemisphere.
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Base de dados:
MEDLINE
Assunto principal:
Circulação Cerebrovascular
/
Sistemas Automatizados de Assistência Junto ao Leito
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Acidente Vascular Cerebral
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Técnicas de Diagnóstico Neurológico
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article