Severe variable deceleration is associated with intestinal perforation in infants born at 22-27 weeks' gestation.
J Matern Fetal Neonatal Med
; 22(3): 259-64, 2009 Mar.
Article
em En
| MEDLINE
| ID: mdl-19330711
ABSTRACT
OBJECTIVE:
Intestinal perforation in extremely premature infants is an important cause of death. The aim of the study was to identify fetal heart rate patterns, which were associated with intestinal perforation.METHODS:
A retrospective cohort study was performed in 92 women who delivered at 22-27 weeks' gestation at a tertiary center in Miyazaki. They delivered 74 singletons, 17 twins and one triplet. Intrapartum fetal heart rate monitoring charts of at least 2-h were examined. Intestinal perforation was diagnosed by the clinical manifestations and operative findings. Multiple logistic regression analysis was used to compare between intestinal perforation group and non-perforation group.RESULTS:
Of the 111 neonates, 17 had intestinal perforation. Severe variable deceleration (p < 0.05), prematurity (p < 0.05), postnatal corticosteroid (p < 0.05), intraventricular hemorrhage of grade III or IV (p < 0.01) and poor survival (p < 0.05) were more frequent in infants with perforation than in the 94 without perforation. Multivariate analysis adjusted for the other risk factors revealed that only severe variable deceleration remained as a risk factor (odds ratio 3.7; 95% CI 1.1-12.1; p = 0.03).CONCLUSIONS:
Intrapartum severe variable deceleration is associated with subsequent intestinal perforation in extremely premature infants, suggesting that preventing prolonged periods of these decelerations may prevent intestinal perforation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Frequência Cardíaca Fetal
/
Doenças do Prematuro
/
Perfuração Intestinal
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article