Vanadium-catalyzed asymmetric epoxidation of allylic alcohols in water.
J Org Chem
; 74(9): 3350-5, 2009 May 01.
Article
em En
| MEDLINE
| ID: mdl-19344136
ABSTRACT
Asymmetric V-catalyzed epoxidation of allylic alcohols can be carried out in water with chiral ligands, which incorporate sulfonamide and hydroxamic acid fragments. Furthermore, the reaction, notorious for its ligand-deceleration effect, in water turned into the ligand-accelerated process. By using this aqueous protocol, a range of allylic alcohols were epoxidized with up to 94% ee.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vanádio
/
Água
/
Propanóis
/
Compostos de Epóxi
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article