The Santa Lucia strain of Plasmodium falciparum in Aotus monkeys.
Am J Trop Med Hyg
; 80(4): 536-40, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19346371
ABSTRACT
The Santa Lucia strain of Plasmodium falciparum was studied in 150 Aotus lemurinus griseimembra, 30 A. azarae boliviensis, 103 A. nancymaae, and 121 A. vociferans monkeys. All four of these splenectomized hosts supported the production of gametocytes infective to Anopheles freeborni mosquitoes. Transmission through sporozoites from An. freeborni, An. stephensi, An. maculatus, and An. albimanus mosquitoes was successful to all four species of Aotus on a total of 100 occasions with a median pre-patent period of 21 days. For the production of infective mosquitoes for vaccine challenge studies, A. l. griseimembra and A. vociferans were the most predictable hosts.
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Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
/
Malária Falciparum
/
Aotidae
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article