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Daily consumption of Reliv Glucaffect for 8 weeks significantly lowered blood glucose and body weight in 50 subjects.
Belcaro, Gianni; Cesarone, Maria; Silvia, Errichi; Ledda, Andrea; Stuard, Stefano; G, Vinciguerra; Dougall, Mark; Cornelli, Umberto; Hastings, Carl; Schönlau, Frank.
Afiliação
  • Belcaro G; Irvine3 Vascular Labs and Physiology, Department of Biomedical Sciences, Gabriele D'Annunzio University, Chieti-Pescara, Italy.
Phytother Res ; 23(12): 1673-7, 2009 Dec.
Article em En | MEDLINE | ID: mdl-19405040
ABSTRACT
A public change to healthier lifestyles with more physical activity and better nutrition, including caloric restriction, is required to address the obesity epidemic. Weight loss can be achieved by caloric restrictions; current research suggests that this may be achieved by consumption of slowly absorbed carbohydrates owing to the resulting prolonged satiety. Our rationale was to prolong the satiety of overweight volunteers by supplementation with a proprietary formulation Glucaffect which delays absorption of carbohydrates. Glucaffect provides potent alpha-glucosidase inhibitors of herbal source such Pycnogenol, Madeglucyl and various others which obstruct absorption of carbohydrates, such as starch. Fifty overweight subjects received either Glucaffect or an inactive control product for eight weeks. Consumption of Glucaffect was found to statistically significantly lower blood-fasting glucose from baseline 145.3 mg/dL to 101.1 mg/dL (-30.4%) and Hba1c from 7.59% to 6.33% as compared to the control group where values decreased only marginally. The weight and the body mass index (BMI) decreased significantly from an average of 88.5 kg (BMI 26.8 kg/m2) to 81.3 kg (BMI 24.5 kg/m2) as compared to the control group. In conclusion, Glucaffect enabled subjects with metabolic syndrome to achieve healthy BMI and blood glucose levels. Glucaffect was well tolerated and no subject dropped out.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Redução de Peso / Fármacos Antiobesidade / Hipoglicemiantes / Fitoterapia Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Redução de Peso / Fármacos Antiobesidade / Hipoglicemiantes / Fitoterapia Idioma: En Ano de publicação: 2009 Tipo de documento: Article