FlexServ: an integrated tool for the analysis of protein flexibility.
Bioinformatics
; 25(13): 1709-10, 2009 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-19429600
ABSTRACT
SUMMARY:
FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemann's indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics.AVAILABILITY:
http//mmb.pcb.ub.es/FlexServ; http//www.inab.org
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Software
/
Proteínas
/
Biologia Computacional
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article