Quantitative 35Cl nuclear quadrupole resonance in tablets of the antidiabetic medicine Diabinese.
Anal Chem
; 81(13): 5574-6, 2009 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-19492808
ABSTRACT
Pulsed (35)Cl nuclear quadrupole resonance (NQR) experiments have been performed on 250-mg tablets of the antidiabetic medicine Diabinese to establish the conditions needed for noninvasive quantitative analysis of the medicine in standard bottles. One important condition is the generation of a uniform radio-frequency (RF) field over the sample, which has been achieved by two designs of sample coil one of variable pitch, and the other a resonator that has been fabricated from a single turn of copper sheet with a longitudinal gap bridged by tuning capacitors. The results from blind tests show that the number of tablets in a bottle could be predicted to within +/-3%.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Espectroscopia de Ressonância Magnética
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Clorpropamida
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Hipoglicemiantes
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article