[Evaluation of HbA1c using different methods in haemoglobin variant, Hb J-Bangkok].
Rinsho Byori
; 57(5): 431-5, 2009 May.
Article
em Ja
| MEDLINE
| ID: mdl-19522248
ABSTRACT
A 31-year-old Japanese man with haemoglobin variant, Hb J-Bangkok [beta56 (D7) Gly-->Asp], was found by discrepant values between HbA1c and glycated-albumin. We measured HbA1c using three different methods, HPLC, enzyme assay and turbidimetric immunoassay. HbA1c value measured by HPLC was much lower than those by others. Furthermore, we estimated calculated glyco-haemoglobin value measured by high-resolution HPLC, revealing that HbA1c values measured by enzyme assay and turbidimetric immunoassay were comparable with calculated value. When measuring HbA1c value in haemoglobin variant, Hb J Bangkok, enzyme assay and turbidimetric immunoassay are useful methods.
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Base de dados:
MEDLINE
Assunto principal:
Hemoglobinas Glicadas
/
Hemoglobina J
/
Imunoensaio
/
Hemoglobinopatias
/
Nefelometria e Turbidimetria
Idioma:
Ja
Ano de publicação:
2009
Tipo de documento:
Article