Antimalarial compounds from the stem bark of Vismia laurentii.
Z Naturforsch C J Biosci
; 64(3-4): 210-4, 2009.
Article
em En
| MEDLINE
| ID: mdl-19526714
ABSTRACT
A phytochemical study of the stem bark of Vismia laurentii resulted in the isolation of a tetracyclic triterpene, tirucalla-7,24-dien-3-one (1), and seven other known compounds 3-geranyloxyemodin (2), vismiaquinone A (3), vismiaquinone B (4), bivismiaquinone (5), epifriedelinol (6), betulinic acid (7) and stigmasta-7,22-dien-3-ol (8). The structure of all these compounds was elucidated by spectroscopic means. The stem bark extract and compounds 1 and 3 showed good antimalarial activity against the W2 strain of Plasmodium falciparum.
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Base de dados:
MEDLINE
Assunto principal:
Caules de Planta
/
Clusiaceae
/
Antimaláricos
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article