Persistent toxoplasma bradyzoite cysts in the brain: incidental finding in an immunocompetent patient without evidence of a toxoplasmosis.
Clin Neuropathol
; 28(3): 210-2, 2009.
Article
em En
| MEDLINE
| ID: mdl-19537140
ABSTRACT
We report on a 72-year-old patient in whom autopsy demonstrated incidentally intracerebral Toxoplasma gondii cysts, locally restricted in the occipital lobe, in association with only a few CD4+ and CD8+ T cells and a mild microglial activation. The patient was HIV-negative. Serologically, there was no evidence for an active inflammation (Toxoplasma gondii specific antibody IgG-positive, IgM-negative). This unusual observation may indicate that in patients with sepsis, who may yield to a state of immunodysbalance, a focal reactivation of parasites may ensue in the absence of conditions predisposing for opportunistic infection.
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Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Toxoplasmose Cerebral
/
Sepse
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article