Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins.
J Pept Sci
; 15(10): 629-33, 2009 Oct.
Article
em En
| MEDLINE
| ID: mdl-19634177
ABSTRACT
This manuscript shows that ACN can be an excellent choice for the coupling of hindered amino acids as illustrated by the coupling of Fmoc-amino acids on free amino acids anchored on a BAL synthesis. Furthermore, ACN can be a good alternative for solid-phase peptide synthesis in the absence of DMF (washings, removal of Fmoc, and coupling).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acetonitrilas
/
Peptídeos
/
Polietilenoglicóis
/
Poliestirenos
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article