Bacterial screening of platelet concentrates: results of 2 years active surveillance of transfused positive cultured units released as negative to date.
Vox Sang
; 97(4): 355-7, 2009 Nov.
Article
em En
| MEDLINE
| ID: mdl-19682347
ABSTRACT
BACKGROUND:
The BacT/ALERT system for bacterial monitoring of platelet concentrates (PCs) was introduced in the Netherlands in 2001. Samples are cultured for 7 days, and as a result of the short shelf-life of PCs, they are usually released as 'negative to date'. Therefore, some of the PCs have already been transfused at the moment of a positive signal in continued cultures in the BacT/Alert. It is unclear, however, whether these PCs are associated with more transfusion reactions.METHODS:
During a 2-year period clinical data were collected from all patients who received PCs released as 'negative to date' but with a positive bacterial culture after being transfused.RESULTS:
Data of 158 patients who received PCs with confirmed positive bacterial culture tests were analysed. Two patients developed a transfusion reaction. In both PCs, Propionibacterium was cultured. The imputability as related to the transfusion was classified as unlikely in both patients.CONCLUSION:
Two of 158 transfusions of PCs released as 'negative to date', but with a confirmed positive BacT/ALERT result, were initially associated with transfusion reactions. However, the imputability of both reactions was low.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Propionibacterium
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Plaquetas
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Técnicas de Tipagem Bacteriana
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Plaquetoferese
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Transfusão de Plaquetas
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article