Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers after renal transplantation.
Clin Transplant
; 23 Suppl 21: 33-6, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19930314
ABSTRACT
Renin-angiotensin system blockade retards the progression of diabetic and non-diabetic chronic kidney disease of the native kidneys. Though most patients suffer from a significant renal insufficiency (chronic kidney disease stage III) and a concomitant heart disease after renal transplantation, there is up to now no evidence supporting the use of inhibitors of the renin-angiotensin system in these patients. We wish to summarize the available evidence on the use of inhibitors of the renin-angiotensin system after renal transplantation. We specifically discuss potential beneficial as well as adverse effects of a renin-angiotensin system blockade. In addition, we review their influence on morphologic and biochemical markers as well as on renal function, graft and patient survival after renal transplantation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Inibidores da Enzima Conversora de Angiotensina
/
Transplante de Rim
/
Bloqueadores do Receptor Tipo 1 de Angiotensina II
/
Hipertensão
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article