Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate.
Gynecol Obstet Invest
; 69(2): 131-5, 2010.
Article
em En
| MEDLINE
| ID: mdl-19996602
ABSTRACT
AIM:
We studied morphologic modifications of the endometrium induced by leuprorelin acetate, a gonadotropin-releasing hormone agonist, in women with uterine myomata.METHODS:
Transmission and scanning electron microscopy observations were performed after 2 or 6 cycles of therapy (every 28 days).RESULTS:
A near-normal endometrium was observed after 2 months of therapy, while treatment with 6 cycles of leuprorelin acetate induced a uniform morphologic regression of the uterine mucosa.CONCLUSIONS:
The study demonstrates that leuprorelin acetate induces a unique and time-dependent regression of the endometrial mucous membrane.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uterinas
/
Hormônio Liberador de Gonadotropina
/
Leuprolida
/
Antineoplásicos Hormonais
/
Endométrio
/
Leiomioma
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article