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The hepatocyte growth factor receptor (MET) gene is not associated with refractive error and ocular biometrics in a Caucasian population.
Schache, M; Chen, C Y; Dirani, M; Baird, P N.
Afiliação
  • Schache M; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia. mschache@unimelb.edu.au
Mol Vis ; 15: 2599-605, 2009 Dec 04.
Article em En | MEDLINE | ID: mdl-20011629
PURPOSE: The purpose of this study was to determine if genetic variants in the hepatocyte growth factor receptor (MET) gene are associated with refractive error and ocular biometric measures in a Caucasian cohort. METHODS: A case-control association study using 818 Caucasian adults (37.2% male, 62.8% female; average age: 51.21+/-17.17 years) was undertaken. All individuals were genotyped for 16 tag single nucleotide polymorphisms (tSNPs) across the MET gene region. Myopia was defined as -0.5 DS or worse in both eyes and divided into high myopia (
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Erros de Refração / Biometria / Proteínas Proto-Oncogênicas c-met / Predisposição Genética para Doença / População Branca / Olho Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Erros de Refração / Biometria / Proteínas Proto-Oncogênicas c-met / Predisposição Genética para Doença / População Branca / Olho Idioma: En Ano de publicação: 2009 Tipo de documento: Article