An enantioselective approach to highly substituted tetrahydrocarbazoles through hydrogen bonding-catalyzed cascade reactions.
Org Lett
; 12(5): 1140-3, 2010 Mar 05.
Article
em En
| MEDLINE
| ID: mdl-20146508
ABSTRACT
A hydrogen bonding-mediated double Michael addition-aromatization cascade of 2-propenylindoles and nitroolefins has been disclosed. The methodology allows an efficient synthesis of diverse and structurally complex tetrahydrocarbazoles in good to excellent enantioselectivities and diastereoselectivities.
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Base de dados:
MEDLINE
Assunto principal:
Carbazóis
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article