Paraneoplastic syndromes and the kidney.
Saudi J Kidney Dis Transpl
; 21(2): 222-31, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-20228504
ABSTRACT
A paraneoplastic syndrome is defined as a group of symptoms that develop when substances released by some cancer cells disrupt the normal function of the surrounding cells and tissue. Paraneoplastic renal syndromes are diseases that indirectly compromise tubular and glomerular function by electrolyte imbalance, hormone-producing tumors or deposition of antigen-antibody complexes in the glomeruli. In order to describe the most common paraneoplastic syndromes, which may compromise the renal function, an extensive review was performed of papers, including case reports, guidelines, meta-analysis and other scientific publications. Renal function can be affected by many paraneoplactic syndromes hypercalcemia in malignancies, syndrome of inappropriate secretion of antidiuretic hormone, tumor lysis syndrome, renin-producing tumors and paraneoplastic glomerulopathies. An early diagnosis and effective treatment might improve quality of life and alter prognosis of these patients.
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Base de dados:
MEDLINE
Assunto principal:
Síndromes Paraneoplásicas
/
Rim
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Nefropatias
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article