Choroidal metastasis with adenocarcinoma of the lung treated with gefitinib.
Eur J Ophthalmol
; 20(5): 963-5, 2010.
Article
em En
| MEDLINE
| ID: mdl-20383850
ABSTRACT
PURPOSE:
To report a case of bilateral regression of choroidal metastasis with adenocarcinoma of the lung treated with gefitinib.METHODS:
Retrospective case review of a 68-year-old woman with pulmonary adenocarcinoma with choroidal metastasis who presented with visual loss in the left eye as the initial manifestation. Her visual acuity was 6/6 in the right eye and 6/60 in the left eye before the start of gefitinib administration. Best-corrected visual acuity and spectral-domain optical coherence tomography were compared between baseline and 3 months after treatment.RESULTS:
Best-corrected visual acuity in the left eye had improved to 6/30 3 months after oral gefitinib. The elevated lesions of the right eye disappeared, with decrease of subretinal fluid and retinal pigment epithelial atrophy. Spectral-domain optical coherence tomography showed that subretinal fluid of the left eye was also reduced.CONCLUSIONS:
Oral gefitinib could be effective for regression of choroidal metastasis in patients with adenocarcinoma of the lung and provides a potential treatment option.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Quinazolinas
/
Adenocarcinoma
/
Neoplasias da Coroide
/
Neoplasias Pulmonares
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article