An efficient method for the synthesis of unsymmetrical 2,2'-bis(pyrrolyl)alkanes.
Org Biomol Chem
; 8(9): 2204-11, 2010 May 07.
Article
em En
| MEDLINE
| ID: mdl-20401397
ABSTRACT
A new strategy for the preparation of unsymmetrical 2,2'-bis(pyrrolyl)alkanes has been developed. It involved the condensation of pyrrole derivatives onto N-benzylhydroxylamines in the presence of HCl. This two-step procedure provided access to a wide variety of 2,2'-dipyrromethanes (3a-m). It has also been extended to the synthesis of tripyrromethanes 4a-d and of N-confused dipyrromethanes 6a-d.
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1
Base de dados:
MEDLINE
Assunto principal:
Pirróis
/
Alcanos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article