[Studies on the chemical constituents of Rumex crispus].

ABSTRACT

OBJECTIVE: To study the chemical constituents of Rumex crispus. METHODS: Compounds were isolated and purified repeatedly by silica gel, Sephadex gel and ODS C18 column chromatographies, and structure identifications of compounds were carried out by physical, chemical methods and spectral data. RESULTS: Fifteen compounds were obtained from the petroleum ether and ethyl acetate fractions of R. crispus, and were identified as beta-sitosterol(1), hexadecanoic acid(2), hexadecanoic-2,3-dihydroxy propyleste(3), chrysophanol(4), physcion(5), emodin(6), chrysophanol-8-O-beta-D-glucopyranoside(7), physcion-8-O-beta-D-glucopyranoside(8), emodin-8O-beta-D-glucopyranoside(9), gallic acid(10), (+)-catechin(11), kaempferol(12), quercetin(13), kaempferol-3-O-alpha-L-rhamnopyranoside(14), quercetin-3-O-alpha-L-rhamnopyranoside(15). CONCLUSION: Compounds 3,8-12,14 and 15 are obtained from R. crispus for the first time.