Type 1 diabetes mellitus and hyperadrenocorticism in a ferret.
Vet Res Commun
; 34 Suppl 1: S107-10, 2010 Jun.
Article
em En
| MEDLINE
| ID: mdl-20446034
ABSTRACT
Diabetes mellitus (DM) was diagnosed in a 6-year-old neutered male ferret with polyuria/polydipsia, symmetrical alopecia, and weight loss. Laboratory tests revealed severe hyperglycemia, glucosuria, and increased steroid hormone profile. Abdominal ultrasound revealed a bilateral enlargement of the adrenal glands. Significant clinical improvement was achieved with insulin- and leuprolide acetate-based therapy. After 2 months of therapy, the ferret showed a severe ketoacidosis, and the owner decided to euthanize the animal. Histological findings revealed carcinoma of the left adrenal cortex and cortical hyperplasia of the right adrenal gland. Moderate, chronic, and active pancreatitis with a marked decrease in the number of beta-cells was also present. This is the first reported case of type 1 DM associated with hyperadrenocorticism and chronic pancreatitis in a ferret.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hiperfunção Adrenocortical
/
Diabetes Mellitus Tipo 1
/
Furões
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article