In vitro differential phenotypic characteristics among Type-II Toxoplasma gondii strains from congenital toxoplasmosis in humans.
J Parasitol
; 96(4): 798-9, 2010 Aug.
Article
em En
| MEDLINE
| ID: mdl-20476804
ABSTRACT
In France, more than 80% of human congenital toxoplasmosis is attributable to Toxoplasma gondii strains belonging to the type-II lineage, whereas 3 main lineages have been described in Europe. Cell invasion, parasite replication, and cyst formation of type-II strains isolated from congenital infections were compared in a human cell model. The phenotype patterns of the 4 type-II strains studied differed from each other; the 2 strains responsible for asymptomatic infection formed significantly fewer cysts than the 2 strains isolated from symptomatic toxoplasmosis. The capacity to form cysts was different among the type-II strains studied and may be related to the clinical form.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Toxoplasma
/
Toxoplasmose Congênita
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article