Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis.

Mazereeuw-Hautier, Juliette; Hoeger, Peter H; Benlahrech, Sarah; Ammour, Amir; Broue, Pierre; Vial, Julie; Ohanessian, Gerard; Léauté-Labrèze, Christine; Labenne, Marc; Vabres, Pierre; Rössler, Jochen; Bodemer, Christine

Mazereeuw-Hautier, Juliette; Hoeger, Peter H; Benlahrech, Sarah; Ammour, Amir; Broue, Pierre; Vial, Julie; Ohanessian, Gerard; Léauté-Labrèze, Christine; Labenne, Marc; Vabres, Pierre; Rössler, Jochen; Bodemer, Christine.

Afiliação

Mazereeuw-Hautier J; Dermatology Department, Paul Sabatier University and the Department of Dermatology, Children's Hospital, Toulouse, France. mazereeuw-hautier.j@chu-toulouse.fr

J Pediatr ; 157(2): 340-2, 2010 Aug.

Article em En | MEDLINE | ID: mdl-20488455

ABSTRACT

ABSTRACT

We report the rapid and dramatic efficacy of propranolol in 8 infants with infantile hepatic hemangiomas. The degree of response varied from a significant improvement to a complete resolution of hepatic lesions. Heart failure and hypothyroidism resolved, and hepatomegaly decreased. No side-effects of the drug were noted.

Assuntos

Hemangioma/tratamento farmacológico; Neoplasias Hepáticas/tratamento farmacológico; Propranolol/uso terapêutico; Neoplasias Cutâneas/tratamento farmacológico; Corticosteroides/uso terapêutico; Feminino; Insuficiência Cardíaca/prevenção & controle; Humanos; Lactente; Masculino; Propranolol/farmacologia; Resultado do Tratamento; Vasodilatadores/uso terapêutico

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propranolol / Neoplasias Cutâneas / Hemangioma / Neoplasias Hepáticas Idioma: En Ano de publicação: 2010 Tipo de documento: Article

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