Two cases of treatment with infliximab which replaced long-term home parenteral nutrition and maintained remission in patients with Crohn disease.

ABSTRACT

[Case 1] A 41-year-old man had undergone multiple bowel resections and consequently short bowel syndrome with high-output jejunostomy developed. In July 2008, he started infliximab (IFX) treatment and achieved remission and recovery from cholestatic liver damage following the cessation of home parenteral nutrition (HPN). [Case 2] A 29-year-old woman chose HPN over enteral nutrition because of high-output fecal fluids through a rectovaginal fistula. Treatment with IFX and dietary control reduced her perianal discomfort. In these 2 patients, treatment with IFX successfully replaced long-term HPN which maintained remission, and improved quality of life.