Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population.
Psychiatry Res
; 185(1-2): 16-9, 2011 Jan 30.
Article
em En
| MEDLINE
| ID: mdl-20537399
ABSTRACT
To examine the association of PPP3CC (rs10108011 and rs2461491) and EGR3 (rs3750192) single-nucleotide polymorphisms (SNPs) with Japanese schizophrenia, we performed a case-control association study using 337 patients and 369 healthy controls. As a result, by our moderated cohort-size study, PPP3CC and EGR3 are not genetic risk factors for schizophrenia, whereas meta-analysis showed weak association of rs10108011 with schizophrenia in the Japanese population (odds ratio (OR)=1.12, P=0.01).
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Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
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Calcineurina
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Predisposição Genética para Doença
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Polimorfismo de Nucleotídeo Único
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Proteína 3 de Resposta de Crescimento Precoce
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article