Contribution of intracranial vertebral artery asymmetry to vestibular neuropathy.
J Neurol Neurosurg Psychiatry
; 82(7): 823-5, 2011 Jul.
Article
em En
| MEDLINE
| ID: mdl-20587480
ABSTRACT
OBJECTIVES:
To test the hypothesis that vertebral artery hypoplasia (VAH) may affect the lateralisation of vestibular neuropathy (VN), probably through haemodynamic effect on the vestibular labyrinth.METHODS:
69 patients with unilateral VN were examined with a magnetic resonance angiographic (MRA) and caloric test. 50 healthy subjects served as controls. The diagnosis of intracranial VAH was based on MRA if <0.22 cm in VA diameter and a diameter asymmetry index >40%. The authors then correlated the canal paretic side with the VAH side.RESULTS:
MRA study revealed 29 VAH (right/left 23/6) in VN subjects and six VAH in controls (right/left 5/1). The RR of VAH in VN subjects compared with controls was elevated (RR=2.2; 95% CI 1.8 to 2.8). There was a high accordance rate between the side of VAH and VN. Among 29 patients with unilateral VAH, 65.5% (N=19) had an ipsilateral VN, in which left VAH showed a higher accordance rate (83.3%) than the right side (60.9%). VN subjects with vascular risk factors also had a higher VAH accordance rate (81%) than those without (25%).CONCLUSIONS:
VAH may serve as a regional haemodynamic negative contributor and impede blood supply to the ipsilateral vestibular labyrinth, contributing to the development of VN, which could be enhanced by atherosclerotic risk factors and the left-sided location.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artéria Vertebral
/
Neuronite Vestibular
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article