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Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif.
Su, Dai-Shi; Lim, John J; Tinney, Elizabeth; Tucker, Thomas J; Saggar, Sandeep; Sisko, John T; Wan, Bang-Lin; Young, Mary Beth; Anderson, Kenneth D; Rudd, Deanne; Munshi, Vandna; Bahnck, Carolyn; Felock, Peter J; Lu, Meiquing; Lai, Ming-Tain; Touch, Sinoeun; Moyer, Gregory; Distefano, Daniel J; Flynn, Jessica A; Liang, Yuexia; Sanchez, Rosa; Perlow-Poehnelt, Rebecca; Miller, Mike; Vacca, Joe P; Williams, Theresa M; Anthony, Neville J.
Afiliação
  • Su DS; Department of Medicinal Chemistry and Structural Biology, Merck Research Laboratory, West Point, PA 19486, USA.
Bioorg Med Chem Lett ; 20(15): 4328-32, 2010 Aug 01.
Article em En | MEDLINE | ID: mdl-20609585
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Éteres / Transcriptase Reversa do HIV Idioma: En Ano de publicação: 2010 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Éteres / Transcriptase Reversa do HIV Idioma: En Ano de publicação: 2010 Tipo de documento: Article