Pulmonary nocardiosis developed in a hematopoietic stem cell transplant recipient with bronchiolitis obliterans.
Intern Med
; 49(14): 1441-4, 2010.
Article
em En
| MEDLINE
| ID: mdl-20647664
ABSTRACT
The chronic graft-versus-host disease often requires unceasing immunosuppressive therapy (IST), which increases a risk of infectious complications in hematopoietic stem cell transplantation (HSCT) recipients. We report an adult T-cell leukemia/lymphoma case who developed pulmonary nocardiosis, a rare pulmonary complication, after allogeneic HSCT despite administration of the prophylactic trimethoprim-sulfamethoxazole (TMP/STX). The inhaled corticosteroid in addition to systemic IST had been started for bronchiolitis obliterance 4 months prior to nocardiosis development. The patient was successfully treated with an increased dose of TMP/STX combined with meropenem. Transplantation physicians should keep this rare pulmonary complication in mind during sustained IST.
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Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Infecções Respiratórias
/
Bronquiolite Obliterante
/
Transplante de Células-Tronco Hematopoéticas
/
Nocardiose
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article