Genetics and developmental pathology of twinning.
Semin Fetal Neonatal Med
; 15(6): 313-8, 2010 Dec.
Article
em En
| MEDLINE
| ID: mdl-20663725
ABSTRACT
Twin pregnancy is associated with a high risk of congenital malformations. This review covers the risk of such anomalies in both dizygotic and monozygotic twin pregnancies, and discusses current insights into the associations relating to zygosity, chorionicity and genetic factors. The pathological basis of specific malformations unique to the monochorionic twinning process, including conjoined twinning and twin reversed arterial perfusion (TRAP) sequence, is discussed in more detail, and factors contributing to the higher perinatal mortality rate in multiple pregnancies are addressed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Anormalidades Congênitas
/
Doenças em Gêmeos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article