The challenges of diagnosing thrombotic thrombocytopenic purpura in the critically ill. A case report.
Transfus Apher Sci
; 43(2): 167-70, 2010 Oct.
Article
em En
| MEDLINE
| ID: mdl-20691639
ABSTRACT
Thrombotic thrombocytopenic purpura (TTP) is associated with high mortality rates. TTP may have various and different presentations depending on the organs involved. It is now recognized to be the consequence of reduction of blood levels of the disintegrin and metalloprotease with thrombospondin motifs (ADAMTS)-13. Prompt diagnosis of TTP is paramount, because plasma exchange is the only treatment capable of improving patient's survival with a dual mechanism removal of anti-ADAMTS-13 auto-antibodies and infusion of the active protease available in the fresh frozen plasma. We report herein on the challenges in diagnosing TTP-like complications of post-surgical facial surgery in a young male patient.
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Base de dados:
MEDLINE
Assunto principal:
Púrpura Trombocitopênica Trombótica
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article