Surfactant protein A: an immunoregulatory molecule involved in female reproductive biology.
Int J Biochem Cell Biol
; 42(11): 1779-83, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-20708093
ABSTRACT
Surfactant protein A (SP-A), a member of the collectin family originally described as a major component of lung surfactant, plays an important role in the modulation of lung host defense. A new interest in SP-A is provided by the link between fetal lung development and the timing of labor in the mouse. In the present review, we discuss some of the known features of SP-A such as biological functions, signaling pathways involved and the recent developments showing that SP-A bind and serve as a signal in the female genital tract. Therefore, such reports support a new paradigm involving SP-A as a multifunctional protein in the parturition process.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Reprodução
/
Proteína A Associada a Surfactante Pulmonar
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article