Outbreak of CTX-M-15-producing Klebsiella pneumoniae of sequence type 199 in a Latvian teaching hospital.
APMIS
; 118(9): 713-6, 2010 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-20718724
ABSTRACT
Previous studies on the epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Latvia are lacking. ESBL-producing Klebsiella pneumoniae (n = 32) were subjected to pulsed-field gel electrophoresis (PFGE) and selected isolates to multi-locus sequence typing (MLST). Species identification and susceptibility testing were performed using VITEK2, and sequencing of bla(CTX-M) was performed in selected isolates. PFGE revealed one major clone (n = 23), with most of the isolates derived from the ICU. The clone harboured bla(CTX-M-15), was sequence type 199 and comprised two ertapenem non-susceptible isolates. This is the first report of an ESBL outbreak in Latvia, and calls for increased epidemiological typing of ESBL-producing Enterobacteriaceae, as well as improved infection control routines.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Beta-Lactamases
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Infecções por Klebsiella
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Klebsiella pneumoniae
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article