Insulin-like growth factor-1 and zinc status of goitrous primary-school children in Arak, Islamic Republic of Iran.
East Mediterr Health J
; 16(6): 646-50, 2010 Jun.
Article
em En
| MEDLINE
| ID: mdl-20799593
ABSTRACT
Despite a successful national salt iodinization programme, endemic goitre still persists in Iranian children. In a cross-sectional study in Arak the prevalence of goitre was 5.2% in a sample of 6520 primary-school children. Subsamples of 193 children with goitre and 151 healthy children were assessed for urinary iodine excretion, thyroid hormone profile, insulin-like growth factor-1 (ICF-1) and serum zinc. The mean urinary iodine levels of goitrous children and healthy children were 17.4 microg/dL and 15.3 microg/dL respectively, suggesting that iodine consumption was adequate. No significant differences were found between goitrous and healthy schoolchildren in mean levels of urinary iodine, serum IGF-1 or serum zinc. Other factors need be evaluated to, explain the residual prevalence of goitre.
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Base de dados:
MEDLINE
Assunto principal:
Zinco
/
Fator de Crescimento Insulin-Like I
/
Bócio Endêmico
/
Iodo
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article