Time and space resolved uptake study of silica nanoparticles by human cells.
Mol Biosyst
; 7(2): 371-8, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-20877915
ABSTRACT
A spatio-temporal mapping of the uptake of silica (SiO(2)) nanoparticles of different sizes by lung epithelial cells has been obtained. Based on high control of nanoparticle dispersion in cell media and cell exposure, one obtains reproducible and quantitative time-resolved data using a combination of flow cytometry, fluorescence and electron microscopies. We are thereby able to give a rather detailed account of the journey of SiO(2) nanoparticles from the early events of uptake to their final sub-cellular localization.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dióxido de Silício
/
Nanopartículas
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article