Diels-Alder cycloaddition of o-quinonedimethides and alkylidene-5H-furan-2-ones: new and rapid access to lambertellol cores and arthrinone derivatives.
Org Biomol Chem
; 8(24): 5490-4, 2010 Dec 21.
Article
em En
| MEDLINE
| ID: mdl-20936215
ABSTRACT
An efficient synthesis of deoxy-lambertellols was reported through a highly chemo- and diastereoselective intermolecular Diels-Alder cycloaddition between trans-1,2-disiloxybenzocyclobutenes and 2-methylprotoanemonine. Such transformation with δ-substituted γ-alkylidenebutenolides, to prepare new analogues of these tricyclic spirolactones, which would be very difficult to prepare by other ways, was also studied.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinonas
/
Compostos de Espiro
/
Furanos
/
Naftalenos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article