Using neutron protein crystallography to understand enzyme mechanisms.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 11): 1257-61, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-21041947
ABSTRACT
A description is given of the results of neutron diffraction studies of the structures of four different metal-ion complexes of deuterated D-xylose isomerase. These represent four stages in the progression of the biochemical catalytic action of this enzyme. Analyses of the structural changes observed between the various three-dimensional structures lead to some insight into the mechanism of action of this enzyme.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Xilulose
/
Aldose-Cetose Isomerases
/
Difração de Nêutrons
/
Metais
/
Nêutrons
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article