TBAF-catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: access to arylpyridines and bihetaryl compounds.
Org Biomol Chem
; 9(6): 1768-73, 2011 Mar 21.
Article
em En
| MEDLINE
| ID: mdl-21264409
ABSTRACT
The concomitant use of silver oxide and catalytic amount of TBAF allowed the efficient and chemoselective coupling of readily available 4-chloro- and 4-methyl-2-trimethyl-silyl-pyridines with heteroaromatic and aromatic halides. Based on control experiments, a mechanism involving the formation of a pyridylsilver intermediate and TBAF recycling is postulated.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Óxidos
/
Piridinas
/
Compostos de Prata
/
Compostos de Amônio Quaternário
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article