[The synthesis and anti-inflammatory properties of 7-theophyllineacetic acid derivatives]. / Cercetari privind sinteza si proprietatile antiinflamatoare ale unor derivati ai acidului 7-teofilinilacetic.

ABSTRACT

Some esters of 7-theophyllinylacetic acid were synthetized, characterized physicochemically and tested for their anti-inflammatory properties. As compared to indomethacin, reference anti-inflammatory drug, all synthetized compounds were less toxic. The anti-inflammatory properties are influenced by the nature of the ester group radicals, the more active having ramified alchils.