Preemployment screening for tuberculosis in a large health care setting: comparison of the tuberculin skin test and a whole-blood interferon-γ release assay.
J Occup Environ Med
; 53(3): 290-3, 2011 Mar.
Article
em En
| MEDLINE
| ID: mdl-21346634
ABSTRACT
OBJECTIVE:
Determine the performance of an interferon-γ release assay in a health care occupational surveillance program.METHODS:
From January 11, 2005, through January 31, 2006, all new employees (n = 652) undergoing standard, preemployment evaluation at Mayo Clinic, Rochester, Minnesota were evaluated for tuberculosis using a standard process of symptom screening combined with tuberculin skin test (TST) and QuantiFERON-TB Gold test (QFT-G).RESULTS:
Comparing the results of QFT-G directly to TST, QFT-G showed an overall agreement of 92.5%.CONCLUSIONS:
False-positive TST were the most significant issue affecting agreement, and in a low-tuberculosis prevalence population, the need for an effective strategy offering low false-positive results may be best met by combining the TST with QFT-G.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Pulmonar
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Teste Tuberculínico
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Programas de Rastreamento
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Saúde Ocupacional
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Interferon gama
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Emprego
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article