Double vision: pigment genes do more than just color.
Fly (Austin)
; 5(3): 206-9, 2011.
Article
em En
| MEDLINE
| ID: mdl-21406968
ABSTRACT
The use of P element collections led to the discovery of unanticipated effects from common genetic background mutants white, brown, and rosy in our previously reported model of tauopathy that expresses full-length human tau in the fly eye, in which mutant rosy suppresses mutant white and brown worsening of tau-induced toxicity (Ambegaokar & Jackson, 2010, Genetics, v. 186, p. 435-42). Here we discuss further possible effects of mini-white and evidence for autophagy as a mediator of white enhancement of tau toxicity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pigmentos Biológicos
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Autofagia
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Drosophila
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Olho Composto de Artrópodes
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article