Identification of arginine residues in peptides by 2D-IR echo spectroscopy.
J Phys Chem A
; 115(34): 9731-8, 2011 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-21539337
ABSTRACT
The CN stretching vibrations of the guanidyl group in the arginine dipeptide side chain are examined by two-dimensional infrared spectroscopy. In D(2)O, the spectra display two distinct diagonal peaks. These nearly degenerate modes undergo ultrafast energy transfer. The energy-transfer rate was determined directly from the 2D-IR spectra to be 1/2.1 ps(-1). The cross peaks in 2D-IR arising from the energy transfer provide a definitive identification of arginine in larger proteins. An example of arginine in the transmembrane protein M2, found in influenza viruses, is given.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Arginina
/
Físico-Química
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Proteínas da Matriz Viral
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Dipeptídeos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article