Your browser doesn't support javascript.
loading
A clinical study on the effects and mechanism of xuebijing injection in severe pneumonia patients.
Qi, Fei; Liang, Zhi-Xin; She, Dan-Yang; Yan, Guang-Tao; Chen, Liang-An.
Afiliação
  • Qi F; Department of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, China.
J Tradit Chin Med ; 31(1): 46-9, 2011 Mar.
Article em En | MEDLINE | ID: mdl-21563507
ABSTRACT

OBJECTIVE:

To observe the effects of Xuebijing Injection in patients with severe pneumonia, and to explore the mechanism.

METHODS:

Eighty cases of severe pneumonia are randomly assigned to the Xuebijing treatment (forty cases) and the control group (forty cases), with the same routine therapy provided in both groups. Clinical effective rates, inflammatory factors and organ function were observed in both groups.

RESULTS:

The effective rate was higher in Xuebijing group than that of the control group (80.0% vs. 67.5%, P < 0.05). As compared with the control group, the LDH, alpha1-AG, alpha1-AT levels and the peak body temperature decreased markedly with the Xuebijing treatment going, and the secretion of TNF-alpha, IL-6, IL-8 was suppressed in Xuebijing group; but no significant difference was found in leptin level.

CONCLUSION:

Xuebijing Injection may show a protective effect in patients with severe pneumonia. The mechanism is possibly with the decreased secretion of TNF-alpha, IL-6, and IL-8.
Assuntos
Buscar no Google
Base de dados: MEDLINE Assunto principal: Pneumonia / Medicamentos de Ervas Chinesas Idioma: En Ano de publicação: 2011 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Pneumonia / Medicamentos de Ervas Chinesas Idioma: En Ano de publicação: 2011 Tipo de documento: Article