Color of meconium and interleukin-6.
Indian J Pediatr
; 79(1): 48-51, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-21625842
ABSTRACT
OBJECTIVE:
To test the hypothesis that the color of meconial fluid is associated with inflammatory biomarkers, by determining C-reactive protein (CRP) and Interleukin-6 (IL-6) in serum from the umbilical cord.METHODS:
In this prospective study, the authors selected 30 newborns with meconium-stained amniotic fluid (MSAF) 14 with green/brown 656 R color and 16 with brown/cinnamon 654 R color, and 20 newborns which showed clear amniotic fluid without MSAF (non-MSAF); all newborns were from mothers without risk factors for neonatal sepsis.RESULTS:
IL-6 concentration from umbilical cord blood, [median of 12.9 pg/mL (interquartile range {IQR} 8.7-31.0)] of MSAF-green/brown 656 R increased significantly (p < 0.05) when compared with IL-6 concentration, [median of 9.2 pg/mL (IQR 7.2-12.2)] of newborns with clear amniotic fluid and without meconium. CRP from MSAF-green/brown 656 R was median of 0.5 mg/mL (IQR 0.0-2.7), and median of 1.0 mg/mL (IQR 0.0-5.5) from clear amniotic fluid, without meconium.CONCLUSIONS:
Significant association was found between MSAF-green/brown 656 R and increase in IL-6, with normal CRP values.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteína C-Reativa
/
Interleucina-6
/
Sangue Fetal
/
Mecônio
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article