Au-catalyzed synthesis of 2-alkylindoles from N-arylhydroxylamines and terminal alkynes.
Chem Commun (Camb)
; 47(27): 7815-7, 2011 Jul 21.
Article
em En
| MEDLINE
| ID: mdl-21637891
ABSTRACT
The first gold-catalyzed addition of N-arylhydroxylamines to aliphatic terminal alkynes is developed to access O-alkenyl-N-arylhydroxylamines, which undergo facile in situ sequential 3,3-rearrangements and cyclodehydrations to afford 2-alkylindoles with regiospecificity and under exceptionally mild reaction conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hidroxilamina
/
Alcinos
/
Ouro
/
Indóis
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article