Serum estradiol does not differentiate stress, mixed and urge incontinent women around menopause. A report from the Women's Health in the Lund Area (WHILA) study.
Eur J Obstet Gynecol Reprod Biol
; 159(1): 209-12, 2011 Nov.
Article
em En
| MEDLINE
| ID: mdl-21782314
ABSTRACT
OBJECTIVE:
To outline serum estradiol levels in perimenopausal women with stress, mixed or urge incontinence. We believe the majority of urgency symptoms in perimenopausal women to be caused by a pelvic floor dysfunction and a hypermobility of the bladder neck. If this is the case, there would be no difference in estradiol levels between the groups.SETTING:
University hospital. In the observational Women's Health in the Lund Area study, a subset of 400/2221 women reporting urinary incontinence completed a detailed questionnaire regarding lower urinary tract symptoms and had their serum steroid hormone levels measured. Statistical analyses were made by Chi-square test, nonparametrical tests, ANOVA, multi- and univariate logistic regression analysis.RESULTS:
Stress incontinence was reported by 196, mixed incontinence by 153 and urge incontinence by 43 women; in 369, serumestradiol values were available. Serum estradiol did not differ significantly between stress incontinent (median 49.5 pmo/l, range 2.63-875.4), urge incontinent (median 31.6 pmol/l, range 2.63-460.7) or mixed incontinent women (median 35.5 pmol/l, range 2.63-787.9, p=0.62). Logistic regression analysis correcting for age, parity, hormonal status, smoking, hysterectomy and BMI also failed to show any difference in estradiol levels between the groups (p=0.41-0.58).CONCLUSION:
No significant differences in serum estradiol levels between stress, mixed or urge incontinent perimenopausal women could be demonstrated.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Incontinência Urinária
/
Perimenopausa
/
Estradiol
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article