Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.
Chem Commun (Camb)
; 47(36): 10010-2, 2011 Sep 28.
Article
em En
| MEDLINE
| ID: mdl-21833430
A strategy for the site-specific attachment of 2-deoxy-2-fluorosugars to cysteine and dehydroalanine tagged proteins is reported. When combined with thionation of fluorosugars, such as the widely available (18)F probe 2-deoxy-2-[(18)F]fluoroglucose ([(18)F]FDG), this methodology allows fast and direct access to site-specific [(18)F]FDG-labelled proteins.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas
/
Compostos Radiofarmacêuticos
/
Fluordesoxiglucose F18
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article