Blood pressure values in 8-12 year old children with a history of intrauterine growth retardation.
Isr Med Assoc J
; 13(8): 480-4, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21910372
ABSTRACT
BACKGROUND:
Epidemiological studies have found that intrauterine growth retardation (IUGR) is closely related to hypertension and is associated with a reduced number of nephrons that may be a predisposing factor for the development of hypertension.OBJECTIVES:
To determine whether blood pressure levels of children with a history of IUGR are higher than those of children without IUGR.METHODS:
Diastolic, systolic and mean arterial blood pressure levels were measured in 64 children aged 8-12 years old with a history of IUGR (mean birth weight 1780 +/- 422 g) and compared with 64 age and gender-matched controls who had a normal birth weight (mean 3134 +/- 594 g).RESULTS:
Contrary to previous reports, systolic blood pressure values were significantly lower in the IUGR group compared to the controls (91.6 +/- 11.3 vs. 96.6 +/- 13.9, P = 0.027). There was no difference in diastolic blood pressure values. In the IUGR group, systolic blood pressure correlated significantly with current weight (P < 0.01) and body mass index (P < 0.05), and diastolic blood pressure with weight gain between age 2 and 4 years (P < 0.05). None of the blood pressure values correlated with birth weight.CONCLUSIONS:
Children born with IUGR have lower systolic blood pressure levels than matched controls at age 8-12 years. These data indicate that postnatal weight gain in this group has a greater impact on systolic blood pressure than birth weight.
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Base de dados:
MEDLINE
Assunto principal:
Pressão Sanguínea
/
Retardo do Crescimento Fetal
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article