Advances in zebrafish husbandry and management.

ABSTRACT

The zebrafish has emerged over the past several decades to become a mainstream animal model. While the growth of the use of the fish in basic biomedical research has been characterized by innovation, the methods and tools for fish husbandry, management, and care have been slow to evolve beyond those conceived during the initial establishment of the model system. While these approaches and technologies have certainly served the purposes of the field, they must now be improved to better match the widening scope and scale of research being done in fish. Such advances are made possible by applying new scientific information to the development of more sophisticated approaches for fish husbandry and management, and by considering the lessons learned during the establishment of the rodent model system. This review highlights the recent progress made in various areas of fish husbandry and management and points out new directions for further improvements.