Colonization and infection by colistin-resistant Gram-negative bacteria in a cohort of critically ill patients.
Clin Microbiol Infect
; 17(11): E9-E11, 2011 Nov.
Article
em En
| MEDLINE
| ID: mdl-21939468
ABSTRACT
In recent years there has been renewed interest in colistin for the treatment of infections by multidrug-resistant Gram-negative bacteria, causing concern that increasing use may be accompanied by the emergence of resistance. This is a retrospective cohort study of colonization and infection by colistin-resistant (CR) gram-negative bacteria in critically ill patients. Colonization data were based on surveillance culture results. Among 150 patients, 78 (52%) were colonized by CR Gram-negative bacteria. Among them, 30 (20%) were colonized by Klebsiella pneumoniae isolates and 51 (34%) were colonized by intrinsically resistant to colistin (CIR) enterobacteriaceae. Seven cases of infection were caused by CR K. pneumoniae and 12 cases by CIR strains. The main risk factor for colonization by CR pathogens was colistin treatment.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Infecções por Bactérias Gram-Negativas
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Colistina
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Farmacorresistência Bacteriana
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Bactérias Gram-Negativas
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Antibacterianos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article